Dr. Chih-Ming Ho received his Ph.D. from The Johns Hopkins University and holds the Ben Rich-Lockheed Martin Professor in the UCLA School of Engineering. He served as the UCLA Associate Vice Chancellor for Research from 2001-2005.
Dr. Ho specializes in microfluidics, bio system technologies and turbulence. He is ranked by ISI as one of the top 250 most cited researchers worldwide in the entire engineering category. In 1997, Dr. Ho was inducted as a member of the National Academy of Engineering. In the next year, he was elected as an Academician of Academia Sinica. Dr. Ho holds ten honorary professorships. He has delivered 22 named distinguished lectures and presented 150 plenary/keynote talks in international conferences. Dr. Ho was elected Fellow of the American Physical Society, American Institute for Medical and Biological Engineering as well as American Institute of Aeronautics and Astronautics.
In human disease, many molecular assemblies and pathways in the cellular network behave and interact aberrantly compared with how they act in a healthy state. Intricate cellular functions emerge from mutual interactions of a collection of signaling complexes and difficult to address by studying individual cellular components in isolation. The cellular network changes dynamically as it is subjected to external stimulations. The resultant responses of the bio-system are often not transparent as the result of this innate complexity. The most effective way to handle a problem of the magnitude and complexity as a human disease is to attack it on many fronts, such as by using combinatorial drug therapies. A multidisciplinary paradigm shift concept Feedback System Control (FSC) technology [1, 2, 3] has been developed and can efficiently handle the agile adaptability of biological systems toward environmental stimuli. FSC can provide unprecedented control and insight into the dynamic nature of cellular behavior to enable directed cellular phenotypic and genotypic outcomes for transformative applications in personalized medicine.
- Wong, P.K, Yu, F., Shahangian A., Cheng, G., Sun, R. and Ho, C.M., "Closed-Loop Control of Cellular Functions Using Combinatory Drugs Guided by a Stochastic Search Algorithm", Proceeding of National Academy of Science, Vol. 105, No.13 pp. 5105-5110, 2008
- Ho, D. and Ho, C.M., "System Control-Mediated Drug Delivery Towards Complex Systems via Nanodiamond Carriers", International Journal of Smart and Nano Materials, v. 1. no.1 p,70-81, 2010
- Wang, H., Silva, A., and Ho, C.M., "When Medicine Meets Engineering - Paradigm Shifts in Diagnostics and Therapeutics", Diagnostics, Vol. 3, pp. 126-154, 2013