INVITED SESSIONS

IS M1.1: Biosensors & Nanomedicine

Session Chair: Chien-Fu Chen; Institute of Applied Mechanics, National Taiwan University, Taipei, Taiwan

          This invited session covers topics related to the biosensors and biomaterials for targeting the global heathy issues adopting various nano/microtechnologies, analytical platforms, and biological technologies. 

Towards electrochemical and optical sensors for the determination of COVID-19, Arunas Ramanavicius, State Research Institute Center for Physical and Technological Sciences, Vilnius, Lithuania

Biomedical Applications of Organic Color Centers, Mijin Kim, Molecular Pharmacology Program, Sloan Kettering Institute, New York, USA

Paralleled Droplet Digital Nucleic Acid Amplifications for Pathogen Quantification, Hao Yuan, School of Life Science and Engineering, Southwest Jiaotong University, Chengdu, China

MXene -Based Microneedles for Biosensing and Electrostimulation, Tzu-En (Linna) Lin, Institute of Biomedical Engineering, College of Electrical and Computer Engineering, National Yang Ming Chiao Tung University, Hsinchu, Taiwan

‘Microwebs’: Synthetic Structures Imitating ‘Neutrophil Extracellular Traps (NETs)’, Yang Song, School of Materials Science & Engineering, Shanghai Jiao Tong University, Shanghai, China

IS M2.1: Artificial intelligence implementations in biomedical imaging

Session Chair: Hsieh-Fu Tsai; Technology Development & Innovation Center, Okinawa Institute of Science and Technology Graduate University

          Recent advances in machine learning techniques together with parallel acceleration have contributed to success in artificial intelligence for improving and accelerating biomedical imaging analysis that outperform conventional computer vision analysis. Leveraging artificial intelligence methods for statistical prediction and pattern recognition also present novel interest for application in high throughput image analysis and medical diagnostics. This session focuses on the latest development of artificial intelligence implementation in biomedical imaging.

Automatic Brain Tumor Image Segmentation Using Fast Data Density Functional Theory, Chien-Chang Chen, National Central University, Taiwan

DeepPhenotype: Single-shot segmentation and cell cycle prediction of single cells in phase contrast microscopyPaul Hsieh-Fu Tsai; Tomoya Noma, Amy Q. Shen, Okinawa Institute of Science and Technology Graduate University, Japan

3DeeCellTracker: a deep learning-based method for tracking cells in 3D time lapse images, Chentao Wen; Kotaro Kimura, Nagoya City University, Japan

Segmentation of Cancer Stem Cell using CGAN, Tomoyasu Sugiyama, Tokyo University of Technology, Japan

MR Radiomics in Predicting Response of Vestibular Schwannoma after Gamma Knife Radiosurgery, Chia-Feng Lu, National Yang Ming Chiao Tung University, Taiwan

IS M3.1: Electrical Devise in Biomedical Applications

Session Chair: Bor-Ran Li; Institute of Biomedical Engineering, College of Electrical and Computer Engineering, National Yang Ming Chiao Tung University, Taiwan

          Bioelectronics comprise the development and study of electronic devices that operate as transducers between the signals and functions of biology, and those of conventional electronic processing systems. Bioelectronic devices can be used to regulate the physiology of cells, tissues, and organs in a chemically-specific manner. In addition, they can also be applied to living systems to selectively sense, record, and monitor different signals and physiological states, as well as convert relevant parameters into electronic readout for further processing and decision making.

Realtime 2D imaging of fluorographene and ALD-based sensing membrane for directly cell culture and acidification monitor, Chia-Ming Yang, Institute of Electro-Optical Engineering, Chang Gung University, Taiwan
Rapid and Sensitive Pathogen Detection by Isothermal Amplification Using Janus Particles Enabled Rotational Diffusometry, Han-Sheng Chuang, Department of Biomedical Engineering, National Cheng Kung University, Taiwan
Smart Materials for Future Healthcare and Enabling Technology Applications, Po-Kang Yang, Department of Biomedical Sciences and Engineering, National Central University, Taiwan

New Insights into the Phase Transformation of Graphene Oxide:Biomedical Interfaces, Guan-Yu Chen, Institute of Biomedical Engineering, College of Electrical and Computer Engineering, National Yang Ming Chiao Tung University, Taiwan

Electric-double-layer (EDL) BioFETs for disease diagnosis and cellular response monitoring, Yu-Lin Wang, Institute of Nanoengineering and Microsystems, National Tsing Hua University, Hsinchu, 300 Taiwan

IS M4.1: Printing Technology in Nano-Bio-Medicine

Session Chair: JT Kim; The University of Hong Kong

          Advances in micro/nanoprinting technology are currently making tremendous contributions to diverse fields from healthcare monitoring to organ transplantation. In this invited session, the latest developments on various printing techniques such as inkjet printing, microfluidic dispensing, 3D printing, and so on, and the prospect of their practical applications to diagnosis and therapeutics will be discussed. The meeting will cover a broad range of materials, manufacturing/transfer techniques, and device fabrications related to medicine.

Hydrodynamic confinements: An enabling bioanalytical technology for tumor profiling, Govind Kaigala, IBM Research Europe – Zurich

Bioprinted Human Tissues for Advanced Therapeutics, Jinah Jang, POSTECH

3D-printed Organ Phantoms for Micro-robotics and Minimally-invasive Surgery, Tian Qiu, University of Stuttgart

3D-printed Bio-medical Structural Electronics, Woo Soo Kim, Simon Fraser University

3D Printing of Self-Assembled Dipeptides, Ji Tae Kim, The University of Hong Kong

IS M1.2: Flexible Nanostructured Devices for Sensing and Actuation

Session Chair: Inkyu Park; Professor, Department of Mechanical Engineering, KAIST, Republic of Korea

          In this invited technical session, we discuss recent advancement of flexible sensing and actuation devices based on functional micro/nano-structures. The micro/nano-structures provide unique material and structural characteristics, and therefore facilitate excellent functionalities and superior performances in various applications. Furthermore, by the combination of micro/nano-structures and flexible/stretchable/wearable platforms, we can realize unprecedented performances in sensors and actuators, which can be utilized in numerous fields such as robotics, metaverse, healthcare, and biomedical technologies.

Haptic Biomaterials for Two-Way Communication with Physiological Systems, Prof. Darren Lipomi, University of California at San Diego, USA

Biomedical Electrophysiology Sensing Robot Applications using 3D Printed Dry Electrodes, Prof. Woo Soo Kim, Simon Fraser University, Canada

Electronic Suture for Wireless In-vivo Strain Sensing, Prof. Jaehong Lee, Daegu Gyeongbuk Institute of Science & Technology, Korea

Flexible and Stretchable Wearable Sensors via Engineering Microcracks/Microstructure in Polymer Nanocomposites, Prof. Shuying Wu, Macquarie University, Australia

Soft Nanocomposite Sensors for Human Motion Detection and Healthcare, Prof. Morteza Amjadi, Harriot-Watt University, UK

IS M2.2: Cell mechanics from Research to Applications

Session Chair: Changjin Huang; School of Mechanical and Aerospace Engineering, Nanyang Technological University

          Understanding the mechanical behavior of biological systems paves the way for the development of more effective diagnostics and therapeutics and advanced biomimetic systems. This invited session focuses on the latest findings on cell mechanics from fundamental research to biomimetic and bioinspired biomedical applications.

Strain Rate-Dependent Mechanical Response of Single Cell-Cell Junctions, Ruiguo Yang, Department of Mechanical and Materials Engineering, University of Nebraska-Lincoln, USA

Nano-topography Engineering in Cells, Wenting Zhao, School of Chemical and Biomedical Engineering, Nanyang Technological University, Singapore

Mechanics of Nanoscale Lipid Vesicles, Changjin Huang, School of Mechanical and Aerospace Engineering, Nanyang Technological University, Singapore

Crafting of Extracellular Matrix Mimicry for Transformative Craniofacial Therapies, Tugba Ozdemir, Nanoscience and Nanoengineering Department, South Dakota School of Mines and Technology

Coupled Monitoring and Modulating Neuromuscular Systems, Pingqiang Cai, School of Medicine, Chemistry and Biomedicine Innovation Center, Nanjing University

IS M3.2: Nano/Micro-Technology for Biomedical Applications

Session Chair: Yi-Chiung Hsu; Department of Biomedical Sciences and Engineering, National Central University, Taiwan.

          Nano/Micro-Technology has long been recognized as an emerging strategy for therapy and/or diagnosis of disease. In this session, 3 novel drug nano/micro-carriers for treatment of cancer, nerve recovery, or acnes, as well as 2 advanced nanotechnologies for bio-detections are presented.

Preparation of Multi-function Nanomaterials in Application to Malignant Tumor Treatment, Chian-Hui Lai, Graduate Institute of Biomedical Engineering, National Chung Hsing University, Taiwan.

Development of Magnetic Sample Measurement System for Magnetic Particle Content in Single Living Cell, Tzong-Rong Ger, Department of Biomedical Engineering, Chung Yuan Christian University, Taiwan.

Electromagnetized-Field-Mediated Adaptable Conductive Microporous Hydrogels for Directing Nerve Repair and Brain Function Recovery, Ru-Siou Hsu, Department of Chemistry, Stanford, U.S.A.

Development of Multifunctional Nano-Emulsion for Acne Vulgaris, Kuang-Hung Hsiao1, Chun-Ming Huang1,2,, Yu-Hsiang Lee1,3,

1Department of Biomedical Sciences and Engineering, National Central University, Taiwan

2Department of Dermatology, University of California, San Diego, CA, USA

3Department of Chemical and Materials Engineering, National Central University, Taiwan.

Continuous polymerase chain reaction microfluidics integrating with gold-capped nanoslit sensing chip for Epstein-Barr virus detection, Han-Yun Hsieh, Institute of Applied Mechanics, Department of Engineering, National Taiwan University, Taiwan.

IS M4.2: Engineering Microfluidic Platforms for Bio/Chemical Applications

Session Chair: Sammer Ul Hassan; The University of Hong Kong, Hong Kong SAR

Microfluidics, especially droplet-based microfluidics, has become an enabling technology to perform bio/chemical assays in microsystems. This session aims to present leading scientists working in the fields of microfluidics and droplet-based microfluidics from multidisciplinary backgrounds. The invited speakers will share the cutting-edge technologies and discuss their latest and novel applications. We hope to promote these exciting developments and encourage discoveries across the disciplines to enhance and strengthen the potential of technologies in revolutionizing the fields of point-of-care diagnostics, precision medicine, and biomedical device development.

Picoinjection aided digital reaction unlocking assay for nucleic acid quantification, Prof. Shuhuai Yao, Department of Mechanical and Aerospace Engineering, The Hong Kong University of Science and Technology, Hong Kong SAR

Novel microfluidic technologies for antimicrobial susceptibility testingKangning Ren, Han Sun, Zhengzhi Liu, Chiu-Wing Chan, Yisu Wang, Associate Professor, Department of Chemistry, Hong Kong Baptist University, Hong Kong SAR

Silicon-based micro/nanofluidic devices for cell and biomolecular separation and detection, Levent YOBAS, Associate Professor, Department of Electronic and Computer Engineering, Department of Chemical and Biological Engineering, Hong Kong University of Science & Technology, Hong Kong SAR

Mechanical properties of eutopic endometrial cells as a biomarker for endometriosis, Mohamed Abdelgawad, Associate Professor, Mechanical Engineering Department/College of Engineering, American University of Sharjah, UAE

Pump-free production of nanoscale liposomes using a 3D printed Reactor-In-A-Centrifuge (RIAC), Dario Carugo1, Yongqing He1, Domenico Andrea Cristaldi2, Gareth LuTheryn1,2, Lecturer, 1 Department of Pharmaceutics, UCL School of Pharmacy, University College London, UK, 2 Department of Mechanical Engineering, University of Southampton

IS T1.1: Advance Materials and Manufacturing Technologies

Session Chair: Hui Ying Yang;

High-precision Acoustic Cell Sorting for Biomedical Applications, Ye Ai, Singapore University of Technology and Design

Physics and Modelling of Charge Injection in 2D Material Contact Heterostructures, Yee Sin Ang, Singapore University of Technology and Design, Singapore

Rare Earth Doped Nanoparticles as Dual Modal Imaging Probes, Mei Chee Tan, Singapore University of Technology and Design

Towards an inhuman approach to disease modeling: Tumor-on-a-chip platforms for machine intelligence, Javier G. Fernandez, Singapore University of Technology and Design

Direct Fabrication and Tailoring of Soft Robot Bodies, Pablo Valdivia y Alvarado, Singapore University of Technology and Design

IS T2.1: New Generation of Wearable / Implanted Devices – Leveraging Self-power Technology

Session Chair: Vincent Lee; NUS, Singapore

          In this invited technical session, 5 invited speakers will report recent advances in the implanted devices for applications ranging from retina implants, pacemakers, and peripheral nerves modulations. With the aid of energy harvesting technology and self-powered sensors, various wearable devices and implanted devices are realized in the fashion of self-sustained systems. Moving into the 5G/IoT era, AI-enabled wearable technology will fundamentally change the technology in the healthcare and smart homes.

Optoelectronic biointerface devices for measuring and controlling biological function, Prof. Jun OHTA, Full Professor, IEEE Fellow, Nara Institute of Science and Technology, Japan.

Peripheral Neuromodulation using Triboelectric nanogenerator, Prof. Sanghoon LEE, Assistant Professor, DGIST, Korea.

Self-powered pacemaker supplied by piezoelectric energy harvester, Prof. Bin YANG, Full Professor, Shanghai Jiaotong University, Shanghai, China.

Bipolar-charged rotary electret energy harvester, Prof. Kai TAO, Associate Professor, Department of Microsystem Engineering, Northwestern Polytechnical University, Xi’an, Shaanxi, China.

Progress in the Wearable Sensors and Bioelectronic Medicine, Prof. Chengkuo LEE, Director, Center for Intelligent Sensors and MEMS, National University of Singapore, Singapor.

IS T3.1: Nanomaterials and Nanodevices for Healthcare Applications

Session Chair: Zong-Hong Lin; Institute of Biomedical Engineering, Department of Power Mechanical Engineering, and Frontier Research Center on Fundamental and Applied Sciences of Matters, National Tsing Hua University, Taiwan

          Nanomaterials and nanodevices with various advantages in comparison to conventional ones have triggered increasing research efforts from both industry and academia. Many intelligent or medical nanomaterials and nanodevices have shown their capabilities to continually analyze different activities and help to predict diseases before serious conditions happen. For examples, active/self-powered sensors with no external input power, are mini-sized and lightweight. The development of these smart nanomaterials and nanodevices have pushed their feasible applications in a wide range of fields. This session will attempt to cover the recent achievements of nanomaterials and nanodevices for healthcare applications, which include nanoisozymes, physical/chemical sensors, biosensors, microfluidics for medical & biological applications, and self-powered sensors/systems.

Versatile and advantageous use of spontaneously generated triboelectric signals, Dongwhi Choi, Department of Mechanical Engineering, Kyung Hee University

Human Body-Based Self-Powered Wearable Electronics for Promoting Wound Healing Driven by Biomechanical Motions, Hulin Zhang, College of Information and Computer, Taiyuan University of Technology

Flexible self-powered motion/pressure sensors and their wearable applications, Fang Yi, School of Materials Science and Engineering, Sun Yat-sen University

Design of Wearable Triboelectric Nanogenerator for Self-Powered Healthcare and Biomedical Sensing, Yannan Xie, Institute of Advanced Materials, Nanjing University of Posts and Telecommunications

Towards Continuous Health Monitoring Platforms by Noninvasive enzyme-free biosensors and Triboelectric Nanogenerator based Self-powered systems, Min-Hsin Yeh, Department of Chemical Engineering, National Taiwan University of Science and Technology

IS T1.2: Micro/Nano Technology for Biosensing

Session Chair: Megan Ho; Department of Biomedical Engineering, The Chinese University of Hong Kong

          The COVID-19 pandemic has raised remarkable social awareness on the importance of effective and timely diagnosis to help minimize the risk of contracting and spreading disease-causing pathogens. The advancement of biosensing platforms, built on a concerted effort of micro- and nano-technology, has enabled reliable diagnostics to remedy global health burden. This session is aimed to showcase the recent advances on biosensing ranging from fundamental studies, platform development to translational research.

Novel DNA Biosensor System for Measuring Disease Relevant Enzyme Activities and Drug Screening, Dr. Cinzia Teasauro1; Prof. Birgitta R. Knudsen2, 1VPCIR biosciences, Denmark; 2Department of Molecular Biology, Aarhus University, Denmark

Targeted Sub-Attomole Cancer Biomarker Detection based on Phase Singularity 2D Nanomaterial-Enhanced Plasmonic Biosensor, Prof. Shuwen Zeng, French National Centre for Scientific Research (CNRS), France

Intelligent Digital Microfluidics, Prof. Ya Tang YANG, Department of Electrical Engineering, National Tsing-Hua University, Taiwan

Automatic Mitochondria Detection in Label-Free Live Cell Images Using Deep Learning, Mr. Chan-Min Hsu; Prof. An-Chi Wei, Department of Electrical Engineering, National Taiwan University, Taiwan

Modulation of Membrane Deformation by Shear through Microfluidics for Biomedical Applications, Prof. Megan Yi-Ping Ho, Department of Biomedical Engineering, The Chinese University of Hong Kong, Hong Kong

IS T2.2: Novel Materials for Bio and Robotic Applications

Session Chair: King Lai; Centre for Robotics and Automation, Department of Biomedical Engineering, City University of Hong Kong

          Novel materials have been widely studied and leaded to next-generation micro and nanoscale devices and systems. In this session, we will discuss the stat-of-the-art system with various applications of colloidal quantum dots, graphene, aptamer in biosensing, cellular, photonic and robotic area. To further realize the practical use of these smart and novel materials as functional devices, various way to study and characterize different types of these system has to be developed.

Rapid Detection Using Aptameric Graphene Field-Effect Transistor Biosensors, Guangfu Wu, Department of Biomedical Engineering and Institute of Materials Science, University of Connecticut, United States

Macrophage Modulates the Functions of MSCs in the Presence of Polyethylene Particles, Qi Gao, Department of Orthopedic Surgery, Stanford University, United States

Mechanical Modeling of Cell Adhesion, Yuqiang Fang, School of Mechanical and Aerospace Engineering, Jilin University, China

3D-printed Light-driven Micro Robots, Runhuai Yang, School of Biomedical Engineering, Anhui Medical University, China

Multi-band Infrared Focal Plane Arrays with Colloidal Quantum Dots, Xin Tang, School of Optics and Photonics, Beijing Institute of Technology, Beijing, China

Polyurethane Yarn-based Sensor for Human Motion Monitoring, Xiaoting Li; King Wai Chiu Lai, Centre for Robotics and Automation, Department of Biomedical Engineering, City University of Hong Kong, China

IS T3.2: Nanomedicine in Ophthalmology

Session Chair: Joseph Y. K. Chan; Department of Ophthalmology, The University of Hong Kong, Hong Kong

          Brief session synopsis: The advance in both diagnosis and treatment on eye diseases require the significant input from nanobiomedicine research. In this session, the speakers will share their latest innovations on the novel design of nano-drug delivery systems for improving the current treatment strategies of various retinal diseases, as well as the exploration of the use of microRNA as a therapeutic option to treat glaucoma, the leading cause of irreversible blindness. In addition, the latest biomedical MRI imaging technique will be introduced to better understand the waste clearance mechanisms of the visual system in health and disease in vivo.

Light-triggered drug release for the treatment of retinoblastoma, Weiping Wang, Department of Pharmacology and Pharmacy, The University of Hong Kong, Hong Kong SAR

Development of injectable nanocomposites for intravitreal drug delivery, Victoria R Kearns, Department of Eye and Vision Science, Institute of Life Course and Medical Sciences, University of Liverpool, UK

Biomaterial engineering for controlled release and targeted delivery in the eye, Laurence Lau, Department of Chemical and Biological Engineering, The Hong Kong University of Science and Technology

Dynamic contrast-enhanced imaging of cerebrospinal fluid in the optic nerve, Kevin C. Chan, Departments of Ophthalmology and Radiology, New York University Grossman School of Medicine; Department of Biomedical Engineering, New York University Tandon School of Engineering, New York, New York, USA

Adeno-associated virus-mediated delivery of microRNA-19a enhances axon regeneration and survival in retinal ganglion cells, Heather Mak, Department of Ophthalmology, The University of Hong Kong, Hong Kong

IS T5.2 Biomedical Applications of Fluidics, Hydrogels and Devices

Session Chair: Michinao Hashimoto, Pillar of Engineering Product Development, Singapore University of Technology and Design, Singapore

          This session discusses recent progresses in fluidics, hydrogels and devices in biomedical applications. Relevant technologies in materials development, device fabrication and sample manipulations in micro-to-nano scales. Biomedical applications such as disease diagnostics, drug screening and development, controlled drug delivery and personalized medicine are highlighted.  

Intelligent Magnetic Digital Microfluidic System, Yi Zhang, School of Electronic Science and Engineering, University of Electronic Science and Technology of China, China

Hydrogel Drop-Screen for High-Throughput Cell Functional Heterogeneity Analysis toward Precision Medicine, Chia-Hing Chen, Department of Biomedical Engineering, City University of Hong Kong, Hong Kong, China

Alginate hydrogel microparticles as controlled release carrier of adeno-associated virus for gene therapy, Hiroaki Onoe, Department of Mechanical Engineering, Faculty of Science and Technology, Keio University, Japan

PROTEASE-RESPONSIVE DELIVERY OF AN ANTI-INFLAMMATORY DRUG IN A CHEMICALLY-INDUCED MOUSE MODEL OF SUBCUTANEOUS INFLAMMATION, Tram T. Dang et al., School of Chemical and Biomedical Engineering, Nanyang Technological University, Singapore 637459, Singapore

IceMicroneedles for intradermal delivery of vaccines, Chenjie Xu, Department of Biomedical Engineering, City University of Hong Kong, Hong Kong SAR

IS W1.1: Microfluidics for Diagnostics

Session Chair: Cecil Chen; Department of Biomedical Engineering, City University of Hong Kong

          Microfluidics has been an enabling technology that miniaturizes and automates the diagnostics and therapeutics on a miniaturized platform. Recent success of microfluidics for theranostics has allowed increased sensitivity while maintaining suitability for point-of-care testing for conducting large-scale surveying without increasing medical burden. In this invited session, we provide a venue for discussing an array of microfluidic devices ranging from fluidics, optic, and nanomaterials for investigation of biomedical applications, such as detection of biomarkers and monitoring of treatment efficacy. It is anticipated to bring inspiration propelling researches with new perspectives in this field.

Label-free biosensor of phagocytosis for diagnosing bacterial infections, Bee Luan Khoo, Department of Biomedical Engineering, City University of Hong Kong, Hong Kong

Microengineering Paper’s Wicking Properties for Rapid Flow and Automation in Microfluidic Paper-Based Microfluidic Devices, Hideaki Tsutsui, Departments of Mechanical Engineering and Bioengineering, Stem Cell Center, University of California Riverside, USA

Leukemia-on-a-Chip: Dissecting the Leukemia Niche-associated Mechanisms of Chemotherapy Resistance, Weiqiang Chen, Departments of Biomedical Engineering, Mechanical and Aerospace Engineering, New York University, New York, NY, USA

Microfluidic Magneto-Immunoassay for Rapid, High Sensitivity Protein Quantification, Peter B. Lillehoj, Departments of Mechanical Engineering and Bioengineering, Rice University, USA

Microfluidic Particle Dam for Quantification of Soluble Analytes via Visual Inspection, Ting-Hsuan Chen, Department of Biomedical Engineering, City University of Hong Kong, Hong Kong

IS W2.1: Nano/Molecular Medicine & Engineering

Session Chair: Tzu-En Lin; National Yang Ming Chiao Tung University

          The session is dedicated to providing a forum to discuss the latest developments in all areas of Nano/Molecular Medicine & Engineering.

Marginative Delivery-Mediated Extracellular Leakiness by Biomimetic Nanomedicine, Shang-Hsiu Hu, National Tsing Hua University

Au-doped Cu/Fe@polymer Nanoreactor with Fenton Reaction/Photodynamic Effects

for Synergetic Cancer Therapy, Jiashing Yu, National Taiwan University

Comprehensive study of ion concentration polarization in microfluidics and its application, Yu-Jui Fan, Taipei Medical University

Extrusion 3D Printing a Cell-culture Chip for Drug Screening, Yi-Chen Ethan Li, Feng Chia University

Electrochemical detection and cleaning of the contaminated contact lens by using scanning electrochemical microscopy with soft microelectrode, Tzu-En (Linna) Lin, National Yang Ming Chiao Tung University

IS W3.1: Microfluidics, Analytical Chemistry, and Biosensing

Session Chair: Pin-Chuan Chen; Department of Mechanical Engineering, National Taiwan University of Science and Technology

This session is a multidisciplinary and applications-oriented, which presents the results of original research or development across all of microfluidics fields of interest, particularly in the fields of analytical chemistry and biosensing

Microfluidic Technology for single-cell manipulation and culture, Chia-Hsien Hsu; Institute of Biomedical Engineering and Nanomedicine, National Health Research Institutes, Taiwan

Low-Cost Biosensors Development for Medical Applications and Environmental Monitoring, Yi-Kuang Yen; Department of Mechanical Engineering, National Taipei University of Technology, Taipei, Taiwan

A Self-Powered Glucose Biosensor Operated Underwater to Monitor Physiological Status of Free-Swimming Fish, Shih-hao Huang; Department of Mechanical and Mechatronic Engineering, National Taiwan Ocean University, Keelung, Taiwan

Modular Downstream Two Phase Processing Micro-Reactors, Ya-Yu Chiang; Department of Mechanical Engineering, National Chung Hsing University, Taichung, Taiwan

Rapidly and Simultaneously Quantifying Multiple Biomarkers of L-tyrosine Hydroxylase (TH) Deficiency by Using Paper Microfluidic Devices and Smartphone-Based Analysis System, P.C. Chen; Department of Mechanical Engineering, National Taiwan University of Science and Technology, Taipei, Taiwan

IS W1.2: Advanced plasmonic platform for biosensors

Session Chair: Yu-Jui (Ray) Fan; Taipei Medical University

          The strong enhancement and localization of electromagnetic field in plasmonic systems have found applications in many areas especially in bio-applications. in this session, we focus on the use of plasmonic phenomena in biosensors. With such recent developments, there is the prospect of improving sensitivity and lowering the limit of detection in order to overcome the limitations inherent in ultrasensitive detection of chemical and biological analytes, especially at single molecule levels.

Plasmonic Gold Nanoisland Film as a Substrate for Bacterial Theranostics, Tsung-Rong Kuo, Taipei Medical University

Optimized performances of the NanoBioAnalytical platform for Extracellular Vesicles detection, Wilfrid Boireau, University of Burgundy – Franche-Comté

In situ Au-glycopolymer nanohybridization for SERS-based biosensing and single-cell immunity, Chih-Chia Huang, National Cheng Kung University

Time-Lapse LSPR Detection of Hydrogen Peroxide Secreted from Living Cells Using Plasmonic Gel Films, Yih-Fan Chen, National Yang Ming Chiao Tung University

Microfluidic device integrated nanoslit plasmonic chips for biosensing applications, Yu-Jui (Ray) Fan, Taipei Medical University

IS W2.2: Advances in microswimmers for biomedical applications

Session Chair: Alan Cheng Hou Tsang; The University of Hong Kong

          This invited session covers the recent progress in the development of microswimmers for biomedical applications, such as targeted navigation and targeted drug delivery. The session includes invited talks covering both theoretical and experimental aspects of microswimmers, from biological microswimmers to artificial microswimmers and from individual motion to swarm dynamics.

Collective cargo transport by schooling micro-swimmers, Arnold Mathijssen, University of Pennsylvania

Macrotransport theory for chemotactic microorganisms and diffusiophoretic colloids in hydrodynamic flows, Henry C. W. Chu, University of Florida

Magnetic microswarm: design, targeted delivery and in vivo applications, Li Zhang, The Chinese University of Hong Kong

Nanoswarm from exchange interaction for antimicrobial application, Jinyao Tang, The University of Hong Kong

Smart Artificial microswimmers via reinforcement learning, Alan Cheng Hou Tsang, The University of Hong Kong

IS W3.2: Sensing Single Cell Properties in Microfluidics

Session Chair: Raymond H. W. Lam, Department of Biomedical Engineering, City University of Hong Kong

          This session concludes some recently developed microfluidic strategies for characterizing single-cell properties in different aspects, e.g. drug uptake/resistance, elasticity, zeta potential, cell adhesion strength. Some of these works can offer high-throughput sensing.

High throughput, multiplex single-cell chemical transcriptome profiling for drug deep screening based on drug oligonucleotide-hashing and droplet pairing, Zida Li, Department of Biomedical Engineering, School of Medicine, Shenzhen University

Formation of bacteria and cancer cell pearl chain under dielectrophoresis, Marcos, School of Mechanical and Aerospace Engineering, Nanyang Technological University

How rigid is the flagellar filament of the bacterium Bacillus subtilis? Xinhui Shen, School of Mechanical and Aerospace Engineering, Nanyang Technological University

Revealing cell elasticity clues using a microfluidic cytometer in two-cell entosis, Jifeng Ren, School of Biomedical Engineering, Capital Medical University, Beijing, China

High-throughput electrokinetic sensing for biophysical properties of floating single cells, Raymond H. W. Lam, Department of Biomedical Engineering, City University of Hong Kong